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What is topiramate?

Topiramate is an anticonvulsant medicine commonly used in epilepsy and to treat some mood disorders. However, more recently, it has been established that topiramate has an anti-craving effect in alcoholism.

What is topiramate used for?

Topiramate is used for a number of different purposes, including the treatment of epilepsy, pain syndromes and bipolar affective disorder. However, in this context we are concerned with then use of topiramate to help people with alcohol problems.

How does topiramate work to help people with alcohol problems?

There are several theories indicating how topiramate works to help reduce alcohol consumption. Most agree that topiramate has the potential to reduce craving for alcohol. This effect of topiramate is probably mediated by its ability to moderate the effects of natural brain stimulant chemicals such as glutamate and dopamine.
How well does topiramate work to reduce craving for alcohol?
Most of the research studies to date show that topiramate works better than placebo medicines to reduce alcohol use. It is too early to be clear how effective topiramate might be as compared to other medicines used in this context such as naltrexone and acamprosate.

Are there any side-effects caused by topiramate?

All medicines can cause side-effects and topiramate is no exception. Topiramate can potentially cause a large number of side-effects. If you have any concerns, then these should be discussed with your doctor.

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