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Alcohol Information: Campral

What is Campral?

Campral (acamprosate calcium) is a prescribed medicine often used in the treatment of alcohol dependence, and in particular to reduce cravings for alcohol.

Alcohol cravings occur as part of the syndrome of alcoholism, and Campral has been shown to reduce them. More than this, the research evidence demonstrates that Campral increases the chances of maintaining abstinence after alcohol detox. Additionally, Campral reduces the amount drunk and the number of drinking days in those that continue to drink.

What does Campral do?

Campral reduces the physical and emotional discomfort that occurs when stopping drinking.

Campral is a mild sedative, enhancing the effect of natural chemical sedatives found in the brain. Campral also reduces the effect of natural chemical stimulants found in the brain such as glutamate.

How does Campral work?

Campral reduces the craving for alcohol by affecting the neurons in the brain. Brain neurons become overactive when alcohol is withdrawn from the brain of someone suffering with alcoholism. Campral reduces their activity by altering the transfer rate of calcium.

How effective is campral ?

Research studies show that use of Campral is effective. Campral results in abstinence for 1 in 5 people who would not have achieved abstinence if Campral had not been prescribed.

These studies also show that Campral reduces the amount drunk and the number of days on which alcohol is drunk, for those who do not achieve abstinence.

What are the side effects of campral?

All medicines have the potential to cause side effects and Campral is no exception to this. Campral can cause stomach upset, loss of appetite, dry mouth, diarrhea, flatulence, weakness and dizziness. If a skin rash or tingling or numbness occur in the hands, feet, arms or legs, then this can indicate the occurrence of a severe reaction to Campral – in such cases your doctor should be informed immediately that you are taking Campral. Severe reactions to Campral are rare, and as medicines go in general, Campral is a relatively safe one in terms of its potential to cause serious side effects.

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